TABLE 3.
Tetanus and diphtheria antibodies
| Patient | Tetanus | Diphtheria | ||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Pre-Hi Cy | Post-Hi Cy | Post-Imm | Post-Imm 2 | Pre-Hi Cy | Post-Hi Cy | Post-Imm | Post-Imm 2 | |
| #1 | 0 | 0 | 3.16 | 1.48 | 0 | 0 | 0 | 0 |
| #2 | 5.78 | 5.23 | 9.12 | 6.41* | 0.65 | 0.46 | 1.7 | 0.88* |
| #3 | 7.43 | 7.69 | — | — | 1.26 | 1.62 | — | — |
| #4 | 3.20 | 1.93 | 8.92 | 6.76 | 1.49 | 1.17 | 1.68 | 1.45 |
| #5 | 2.35 | 1.3 | 3.79 | 3.21 | 0 | 0 | 0.42 | 0.3 |
| #8 | 6.14 | 0.96 | 4.8 | 5.39 | 1.45 | 0 | 0.92 | 1.2 |
Tetanus and diphtheria antibodies before and after Hi Cy and after re-immunization. Re-immunization was carried out beginning at 1 year after Hi Cy treatment, but the postimmunization levels were from serum obtained at various time intervals after the first or subsequent re-immunizations. Hi Cy produced reduction of these antibodies against exogenous antigens, but the changes were generally not dramatic. Patients produced antibodies in response to immune stimulation.
*
Indicates a later serum sample without repeat immunization.