Figure 2.

Effect of prolonged synaptic currents on postsynaptic potential. A, B, Representative action potential waveforms recorded from 48 hpf wild-type fast muscle were elicited using voltage command waveforms based on the average synaptic current decays for wild type (A) and twi^+/− (B) shown in Figure 1. The command waveforms are shown in gray and the associated muscle responses are shown in black (n = 5 cells; between 12 and 20 action potentials were averaged for each cell). C, D, Paired current-clamp recordings of motorneuron (gray) and muscle action potentials (black) for 48 hpf wild-type (C; n = 4 pairs; 7–28 action potentials per cell) and twi^+/− (D; n = 6 pairs; 8–26 action potentials per cell) muscle.