Figure 4. .

Intravitreal injection of carcinine protects photoreceptor cells from light-induced damage in mouse retina. (A) Representative pictures of retinal sections were taken at 0.5 mm from the optic nerve head (ONH) to the inferior retina at original magnification ×20. OS, photoreceptor outer segment; IS, photoreceptor inner segment; ONL, outer nuclear layer containing photoreceptor nuclei; OPL, outer plexiform layer, INL, inner nuclear layer; IPL, inner plexiform layer; GCL, ganglion cell layer. (B) The numbers of nuclei in the ONL of PBS- and carcinine-injected eyes were counted on histologic sections from five different mice at 0.5 mm from the ONH to the inferior and superior retina. Averages and SEM were plotted for each group. One-way ANOVA was used to determine the differences between groups, and Bonferroni's post hoc test was performed to test for significance. *P < 0.05; **P < 0.01; ***P < 0.005.