Figure 2. .

Short-term effects of a single dose of ocular hypotensive agents on microbead-induced OHT in mouse. A single eye drop was administered to the mouse right eye on day 7 after intracameral injection of microbeads. (A) Vehicle. (B) Timolol. (C) Latanoprost. (D) Brimonidine. (E) Pilocarpine. (F) Brinzolamide. Measurements of IOPs were conducted at 1, 2, 6, and 24 hours, respectively, after the administration of the eye drops or vehicle. *P < 0.05; **P < 0.01 as compared to the vehicle control–treated group by one-way ANOVA and Bonferroni's test (values are means ± SEM; n = 8/group).