Figure 4. .

Box plots (as in Fig. 2) representing the distribution of raw values at each of the experimental recording sessions. (A) RNFL thickness. (B) Retardance. Values normalized to BL average are plotted in (C) and (D), respectively. (E) RNFL values for EG eyes—expressed relative to fellow control eye of each animal—versus time. For RNFL thickness data: *P < 0.001, versus each BL; †P < 0.05 versus ONH surface topography onset; ‡ P < 0.0001 versus the session prior to ONH onset (median of 20 days prior). For RNFL retardance data: §P < 0.01 versus each BL; #P < 0.0001 versus each BL and the session just prior to ONH onset (median of 9 days prior). (E): *P < 0.01 versus each BL; †P < 0.0001 versus each BL and the session just prior to ONH onset (median of 9 days prior).