Table 1. Dose-dependent changes in SBSN parameters induced by BORIS.

	EV,1 µg /ml dox	BORIS,0 µg/ml dox	BORIS,0.03 µg/ml dox	BORIS,1 µg/ml dox
BORIS expression	−	+	++	+++
BORIS occupancy	−	+	++	+++
SBSN expression	−	+++	++	+
SBSN methylation	++++	+	++	+++
H3K4me3 enrichment	−	+++	+	−
H3Ac enrichment	−	+++	++	−
H3K9me3 enrichment	+	−	−	+
Nucleosome occupancy	+++	−	++	+
Cell growth	−	+++	++	+

Relative changes in different parameters were ranked from (−) to (++++) in according to results from Figures 1, 2, 3, 4, and 5.