Figure 3. Alignment of GmcA sequence with the five most closely related GMCs based on phylogenetic analysis.

Invariant residues are displayed in red background while conserved residues are in yellow. The non-contiguous sequence comprising the substrate binding domain is boxed in red. Table 1 gives the reference for each sequence. Cysteine and histidine residues are marked with blue and green stars, respectively. Residue numbering is for the Aspergillus nidulans GmcA sequence.