Fig. 2.

(a) Interferon (IFN)-γ enzyme-linked immunospot (ELISPOT) responses to dengue virus serotype (DEN)-3 peptide 3-specific line, in the presence or absence of anti-DR, anti-DP or anti-DQ antibodies. (b) IFN-γ ELISPOT responses using DEN-3-specific line, incubated with DEN-3 peptide 3 added directly to T cells and DRB1*1501-expressing L cells pulsed with the peptide and unpulsed L cells used as antigen-presenting cells to the T cell line. (c) IFN-γ ELISPOT responses using three DEN-3-specific lines of three different DRB1*1501 individuals in the presence of varying concentrations of DEN-3 peptide 3.