Fig. 3.
Donor-specific (dsp) CD8 precursor frequency correlates to donor-specific interferon (IFN)-γ enzyme-linked immunospot (ELISPOT) assay. (a) Box-plots show the number of IFN-γ spots measured by ELISPOT of non-rejectors (NR; n = 7) and rejectors (R; n = 7) after mixed lymphocyte culture (MLC) against donor-specific or third-party cells. The box-plot whiskers depict 10–90 percentile. (b) Correlation between number of IFN-γ spots and dsp CD4 precursor frequency (pf) (n = 14). (c) Correlation between number of IFN-γ spots and dsp CD8pf (n = 14). Correlations were calculated using Spearman's test.