Table 1.
Information on demographic data of each treatment arm.
| Variables | CsAfree | CsAlow | CsAreg | P |
|---|---|---|---|---|
| Recipient age (years) | 46 ± 9·8* | 60 ± 11·5* | 50·2 ± 11·6 | <0·05 |
| Recipient gender (male/female) | 2/4 | 3/5 | 3/3 | n.s. |
| LRD (no/yes) | 5/1 | 7/1 | 5/1 | n.s. |
| CIT (min) | 875 ± 368 | 758 ± 372 | 605 ± 356 | n.s. |
| HLA mismatches A, B, DR (mean ± s.d.) | 2·3 ± 1·5 | 2·3 ± 1·9 | 2·5 ± 1·6 | n.s. |
| DGF (no/yes) | 6/0 | 8/0 | 6/0 | n.s. |
| CsA trough level (ng/ml) | ||||
| Month 3 | 125 ± 47 | 127 ± 43 | 135 ± 35·3 | n.s. |
| Month 12 | – | 68 ± 22 | 103 ± 7 | n.s. |
| MPA trough level (ng/ml) | ||||
| Month 3 | 3·1 ± 1·4 | 2·0 ± 0·3 | 2·6 ± 2·6 | n.s. |
| Month 12 | 2·1 ± 1·2 | – | 2·7 ± 1·6 | n.s. |
| EVR trough level (ng/ml) | ||||
| Month 3 | 4·3 ± 1·6 | 4·8 ± 0·9 | – | n.s. |
| Mean sCreatinin (mg/dl) | ||||
| Month 3 | 1·3 ± 0·3 | 1·5 ± 0·5 | 1·6 ± 0·8 | n.s. |
| Month 12 | 1·3 ± 0·4 | 1·6 ± 0·5 | 1·8 ± 0·9 | n.s. |
| Mean GFR (ml/min) | ||||
| Month 3 | 52·7 ± 12·2 | 42·0 ± 10·8 | 49·7 ± 22·1 | n.s. |
| Month 12 | 54·8 ± 14·4 | 42·9 ± 19·7 | 46·8 ± 23·5 | n.s. |
DGF, delayed graft function; CIT, cold ischaemia time; LRD, living related donor; s.d., standard deviation; GFR, glomerular filtration rate; MPA, mycophenolate sodium; CsA, cyclosporin A; HLA, human leucocyte antigen; n.s., not significant.