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. 2012 Jul 6;2:495. doi: 10.1038/srep00495

Figure 2. The kinetics of spleen size in Balb/c mice challenged with aerosol doses of 1.00E+04 cfu (A), 1.00E+05 cfu (B) or 5.00E+05 cfu (C), or an intranasal dose of 1.00E+04 cfu (D) B. melitensis.

Figure 2

Average spleen sizes with standard error of the mean are illustrated at each scheduled euthanasia time point. The average unchallenged control spleen sizes are included on Day 0 in A, B, C, and D for comparison to the challenged animals. * = p < 0.05 compared to control; ** = p < 0.001 compared to control.