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. 2012 Jul 1;3:292–302. doi: 10.7150/jca.4502

Table 4.

Cox proportional hazards models for disease-specific 5-year survival in each decade, stratified by gender.

Women
HR (95% CI)1
Men
HR (95% CI)1
Pinteraction2
Appendix
2000s 1.00 1.00
1990s 1.64 (0.74-3.60) 3.02 (1.02-8.96)
1980s 0.64 (0.23-1.78) 0.97 (0.22-4.21)
1970s 0.62 (0.12-3.22) 1.91 (0.32-11.4)
Ptrend 0.303 0.356 0.344
Small intestine
2000s 1.00 1.00
1990s 1.47 (1.14-1.88) 1.42 (1.11-1.82)
1980s 1.55 (1.15-2.10) 1.83 (1.37-2.44)
1970s 1.66 (1.14-2.43) 2.11 (1.46-3.05)
Ptrend < 0.001 < 0.001 0.168
Rectum
2000s 1.00 1.00
1990s 1.57 (0.98-2.53) 1.41 (0.93-2.14)
1980s 0.91 (0.44-1.87) 1.51 (0.89-2.56)
1970s 1.36 (0.46-3.97) 1.08 (0.50-2.33)
Ptrend 0.107 0.344 0.044
Stomach
2000s 1.00 1.00
1990s 1.32 (0.80-2.18) 0.95 (0.64-1.42)
1980s 1.22 (0.60-2.46) 0.74 (0.40-1.40)
1970s 1.33 (0.53-3.36) 1.43 (0.59-3.50)
Ptrend 0.369 0.758 0.336
Colon
2000s 1.00 1.00
1990s 1.04 (0.82-1.30) 1.18 (0.89-1.56)
1980s 1.27 (0.94-1.71) 1.16 (0.79-1.71)
1970s 1.15 (0.77-1.71) 1.78 (1.16-2.75)
Ptrend 0.054 0.010 0.910

1 Adjusted for age (continuous), stage (localized vs. regional vs. distant), race/ethnicity (non-Hispanic white vs. Hispanic white vs. black vs. Native American vs. Asian), and registry site.

2 P value for interaction term between sex and year of diagnosis (continuous) in Cox proportional hazards model.