Table 7.
Cox proportional hazards models for disease-specific 5-year survival in each decade, stratified by geographic region.
| West HR (95% CI)1 |
South HR (95% CI)1 |
East HR (95% CI)1 |
Midwest HR (95% CI)1 |
Pinteraction2 | |
|---|---|---|---|---|---|
| Small intestine | |||||
| 2000s | 1.00 | 1.00 | 1.00 | 1.00 | |
| 1990s | 1.57 (1.23-2.00) | 1.64 (0.64-4.20) | 1.49 (0.81-2.72) | 1.21 (0.88-1.67) | |
| 1980s | 1.79 (1.28-2.50) | 2.41 (0.88-6.57) | 1.92 (1.02-3.62) | 1.47 (1.05 (2.07) | |
| 1970s | 1.89 (1.25-2.86) | 4.11 (1.18-14.3) | 1.57 (0.70-3.54) | 1.74 (1.14-2.67) | |
| Ptrend | < 0.001 | 0.060 | 0.041 | 0.001 | 0.865 |
| Colon | |||||
| 2000s | 1.00 | 1.00 | 1.00 | 1.00 | |
| 1990s | 0.90 (0.70-1.16) | 2.45 (1.18-5.11) | 0.97 (0.55-1.72) | 1.37 (0.97-1.93) | |
| 1980s | 0.84 (0.54-1.30) | 3.37 (1.46-7.77) | 0.84 (0.38-1.88) | 1.61 (1.10-2.36) | |
| 1970s | 0.72 (0.42-1.22) | 1.85 (0.53-6.51) | 1.70 (0.80-3.65) | 2.01 (1.23-3.29) | |
| Ptrend | 0.553 | 0.012 | 0.165 | 0.002 | 0.028 |
Note: Organ sites with insufficient numbers were excluded from analysis, as were the Southwest and HI/AK regions.
1 Adjusted for age at diagnosis (continuous), stage (localized vs. regional vs. distant), sex (female vs. male), race/ethnicity (non-Hispanic white vs. Hispanic white vs. black vs. Native American vs. Asian), and registry site.
2 P value for interaction term between age (continuous) and year of diagnosis (continuous) in Cox proportional hazards model.