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Plasma decay and hepatic uptake of HDL-PC are not affected by SR-BI deficiency. After intravenous injection of [3H]PC-HDL into SR-BI−/− and wild-type C57Bl/6 mice, plasma radioactivity was measured over a period of 24 h. A, decay curves of 3H from plasma. B, recovery of radiolabel in liver 24 h after injections. Values represent means ± S.E. (error bars) (n = 7 per group).
