MSDC-0602 does not induce hepatic expression of PPARγ target genes.
A, the graphs depict the hepatic expression of PPARγ target genes in lean or DIO mice treated as indicated. n = 8 per group. *, p < 0.05 versus lean mice. B, the graphs depict the hepatic expression of PPARγ target genes in lean or ob/ob mice treated with TZDs. n = 6 per group. *, p < 0.05 versus lean mice. **, p < 0.05 versus lean, ob/ob control, and ob/ob MSDC-0602-treated mice. AU, absorbance units; rosi, rosiglitazone; pio, pioglitazone.