Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
G231D has similar binding affinity for 45AG 1-bp gapped DNA as WT pol β. Various concentrations of WT (filled circles) or G231D (open triangles) protein were incubated with 0.1 nm 45AG DNA (Table 1) for 15 min at room temperature. Data were plotted as fraction product bound versus pol β concentration to obtain the KD(DNA). (WT, 4.1 ± 0.8 nm; G231D, 1.7 ± 0.2 nm).
