FIGURE 1.
The effect of DosR on survival and RNA synthesis of M. smegmatis during hypoxic stationary phase. A, cultures of M. smegmatis mc2155 wild-type, ΔdosR, and ΔdosR/DosRc were grown into hypoxic stationary phase, and their viability was determined by plating at the times indicated. CFU, culture-forming units. B, RNA biosynthesis was measured by determining [3H]uracil incorporation for 24 h. Bq = becquerels. Each data point is the average of measurements from three independent cultures. Error bars are mean ± S.D. *, p < 0.05, Bonferroni post-test following two-way analysis of variance. **, p < 0.001, Bonferroni post-test following two-way analysis of variance.