Table 2.
HR for fatal and non-fatal CVD and SFA in participants in the EURODIAB PCS (n = 2,108)
| Variable | Tertiles of SFA | p value for trend | Per 10 g/day SFA | ||
|---|---|---|---|---|---|
| 1 | 2 | 3 | |||
| Median SFA, g/day (IQR) | 28.6 (24.8–31.0) | 36.6 (34.9–38.5) | 45.4 (42.7–49.5) | 34.8 (25.7–45.5) | |
| n | 702 | 703 | 703 | 2,108 | |
| n cases | 52 | 48 | 48 | 148 | |
| Person-years | 5,101 | 5,090 | 5,118 | 15,309 | |
| Model 1a | 1.00 | 1.04 (0.70, 1.57) | 1.00 (0.67, 1.48) | 0.99 | 0.95 (0.79, 1.13) |
| Model 2b | 1.00 | 1.07 (0.70, 1.62) | 1.03 (0.68, 1.55) | 0.91 | 0.96 (0.80, 1.18) |
| Model 3c | 1.00 | 0.95 (0.62, 1.46) | 0.84 (0.53, 1.32) | 0.43 | 0.85 (0.69, 1.05) |
Values are HR (95% CI) obtained from Cox proportional hazards models according to stratification by tertiles of SFA and continuously per 10 g/day SFA. SFA was adjusted for total energy using the nutrient residual method [31]
aModel 1 adjusted for age (continuous), sex and energy (kJ/day)
bModel 2 additionally adjusted for diabetes duration (years), HbA1c (%), smoking status (no, previous, current), physical activity (physical inactivity, mild physical activity ≥1 time/week, moderate physical activity ≥1 time/week, vigorous physical activity ≥1 time/week) and alcohol (0, >0–<5, 5–<15, 15–<30, 30–<40, ≥40 g/day)
cModel 3 additionally adjusted for total dietary fibre (g/1,000 kcal)