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. Author manuscript; available in PMC: 2013 Jun 8.
Published in final edited form as: Circ Res. 2012 Apr 19;110(12):1596–1603. doi: 10.1161/CIRCRESAHA.112.267732

Figure 3. Active involvement of miR-181c in the mitochondrial RISC complex.

Figure 3

(A) Western blot shows that only Ago 2, and not Dicer or TRBP, is present in the mitochondria. Prohibitin is used as a mitochondrial marker.

qRT-PCR shows both (B) miR-181c and (C) mt-COX1 mRNA, and no other mitochondrial gene products, like (D) mt-COX2 mRNA or (E) 12S rRNA; in the Ago 2 immunoprecipitate from the mitochondrial fraction.