Table 3.

Predictors of Drug-Disease Interactions (RX-DIS) in Community Dwelling VA Patients by Condition/ Disease

	Any Rx-DIS	Dementia Rx-DIS	Falls Rx-DIS	CRF Rx-DIS
Effect	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
Demographic Characteristics
Age	1.0 (0.99–1.0)	0.98 (0.98–0.99)	.98 (.98–.99)	0.97 (0.97–0.98)
Race/ Ethnicity (vs. White)
African American	0.98 (0.95–1.01)	0.88 (0.83–0.92)	1.03 (0.94–1.12)	1.17 (1.11–1.23)
Hispanic	1.25 (1.20–1.31)	1.07 (1.01–1.13)	1.19 (1.07–1.31)	1.35 (1.24–1.46)
Other	0.94 (0.89–1.03)	0.93 (0.82–1.06)	0.98 (0.81–1.19)	1.05 (0.91–1.21)
Women (vs Men)	1.40 (1.31–1.50)	1.43 (1.30–1.57)	1.12 (1.00–1.26)	1.08 (0.90–1.29)
Unmarried (vs. Married)	0.97 (0.95–0.99)	0.93 (0.90–0.96)	0.96 (0.92–1.01)	1.10 (1.05–1.14)
Health Status Factors
Number of Unique Medications	1.09 (1.09–1.09)	1.13 (1.12–1.13)	1.09 (1.08–1.09)	1.04 (1.04–1.05)
Selim Physical	0.97 (0.97–0.98)	0.96 (0.96–0.97)	0.91 (0.90–0.92)	0.99 (0.98–1.00)
Selim Mental Health (vs. 0)
1	1.63 (1.59–1.67)	1.17 (1.13–1.21)	2.08 (1.96–2.20)	1.01 (0.06–1.06)
2 or more	2.36 (1.28–2.43)	1.33 (1.27–1.39)	3.50 (3.28–3.74)	1.19 (1.10–1.28)
Access To Care Factors
Not exempt from copay (vs Exempt)	0.78 (0.75–0.80)	0.85 (0.82–0.89)	0.75 (0.70–0.81)	0.76 (0.60–0.80)
Geriatric Care	1.01 (0.97–1.06)	0.68 (0.64–0.71	1.26 (1.16–1.36)	0.69 (0.62–0.77)
Primary Care Visits (vs. 0–1)
2–4	1.12 (1.08–1.17)	1.28 (1.22–1.34)	0.94 (0.86–1.03)	1.38 (1.29–1.49)
5+	1.21 (1.16–1.26)	1.31 (1.24–1.38)	0.89 (0.80–0.98)	1.47 (1.36–1.59)

Rx-DIS: Drug Disease Interaction

CRF: Chronic Renal Failure

OR: Odds Ratio

CI: Confidence Interval