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. 2012 Jun;2(6):120072. doi: 10.1098/rsob.120072

Table 1.

Parameters of activation and inactivation from Boltzmann fits (millivolts) to the curves produced from INa in myocytes from the LV and RV of WT and Scn5a+/− hearts (n = 17 for activation; n = 12 for inactivation for each group).

activation
inactivation
V1/2 k V1/2 k
WT LV −58.88 ± 2.85 3.65 ± 0.66 −74.64 ± 1.83 7.95 ± 0.62
WT RV −60.42 ± 3.04 4.14 ± 0.42 −75.35 ± 1.72 7.21 ± 0.60
Scn5a+/− LV −64.61 ± 2.96 3.44 ± 0.78 −84.16 ± 1.53a 6.56 ± 0.71
Scn5a+/− RV −63.69 ± 3.40 5.46 ± 0.93 −91.12 ± 1.64a,b 6.61 ± 0.74

aSignificant effect of genotype.

bSignificant effect of cardiac ventricle.