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. 2012 Jun;2(6):120072. doi: 10.1098/rsob.120072

Table 2.

Parameters of activation and inactivation from Boltzmann fits (millivolts), and the time constants of inactivation from the double exponential fit to the curves produced from Ito in myocytes from the LV and RV of WT and Scn5a+/− hearts (n = 14 for each group).

activation
inactivation
V1/2 k V1/2 k
WT LV −11.06 ± 2.54 14.26 ± 3.24 −42.72 ± 1.86 9.18 ± 1.10
WT RV −9.07 ± 2.85 17.24 ± 3.21 −46.40 ± 1.72a 7.80 ± 0.92
Scn5a+/− LV −9.58 ± 3.20 14.15 ± 3.95 −37.13 ± 0.91b 11.30 ± 0.70
Scn5a+/− RV −15.57 ± 3.44 20.69 ± 3.55 −42.98 ± 1.01a,b 10.15 ± 0.73

aSignificant effect of cardiac ventricle.

bSignificant effect of genotype.