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ASIC channels recruit P40S STOML3 mutant protein to vesicles. (a) Overexpression of ASIC2a in sensory neurons leads to a relocalization of P40S STOML3 to the ASIC2a-positive vesicular compartment. (b) Overexpression of ASIC3 recruits P40S STOML3 to vesicles but to a lesser extent that ASIC2a. (c,d) Overexpression of stomatin (c) or wild-type STOML3 (d) does not alter the cytoplasmic localization of P40S STOML3. (a–d) Scale bars, 10 µm.
