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H. hepaticus-induced DNA and RNA damage in colon. Rag2-/- mice were infected with H. hepaticus (H.h.) and colon tissue was isolated at 10 and 20 w p.i. for DNA and RNA damage analyses, as described in Materials and Methods. The figure contains data for damage products showing largest increases or decreases, with the complete dataset shown in SI Appendix, Tables S2 and S3. Statistical analysis is presented in box plots as described in Fig. 1.
