Table 2.

Plasma concentration of total aminothiols (glutathione, homocysteine, cysteine and cysteinylglycine) at baseline and after the 28-day treatment with fenofibrate or placebo

Parameter	Healthy controls*	Baseline	After Placebo	After Fenofibrate
Glutathione [nmol/mL]	11.9 ± 4.9	5.6 ± 1.4	5.6 ± 1.6	6.5 ± 1.7#
Homocysteine [nmol/mL]	11.3 ± 3.2	24.2 ± 12.0	26.9 ± 13.1	29.4 ± 20.2##
Cysteine [nmol/mL]	275 ± 99	535 ± 105	552 ± 107	542 ± 106
Cysteinylglycine [nmol/ml]	25 ± 7	58 ± 12	56 ± 10	56 ± 14

* healthy controls – historic cohort from Bald E et al. [19]

# p = 0.02 vs baseline; ## p = 0.04 vs baseline