Table 3.

Plasma concentration of total free aminothiols (glutathione, homocysteine, cysteine and cysteinylglycine) at baseline and after the 28-day treatment with fenofibrate or placebo

Parameter	Healthy controls*	Baseline	After Placebo	After Fenofibrate
Glutathione [nmol/mL]	5.3 ± 1.2	3.3 ± 0.9	3.4 ± 1.1	4.2 ± 1.4#$
Homocysteine [nmol/mL]	2.6 ± 1.7	6.6 ± 3.9	7.8 ± 5.0	9.0 ± 7.4##
Cysteine [nmol/mL]	47 ± 22	160 ± 48	163 ± 47	167 ± 51
Cysteinylglycine [nmol/ml]	7 ± 2	24 ± 4.5	23 ± 4	25 ± 7

* healthy controls – historic cohort from Bald E et al. [19]

# p = 0.01 vs baseline; $ p = 0.02 vs placebo

## p = 0.04 vs baseline