TABLE 6.
Logistic Regression Models Testing Effects of Chlorpyrifos on the Odds of Mental Delay at 12, 24, and 36 Months, Adjusted for Race, Gender, Gestational Age, Maternal Education, Maternal IQ, ETS Exposure, and Home Environment
| Variable | Odds Ratio (95% CI) | ||
|---|---|---|---|
| Model 1: 12 mo | Model 2: 24 mo | Model 3: 36 mo | |
| Prenatal exposures | |||
| ETSa | 0.58 (0.25–1.33) | 1.26 (0.70–2.56) | 1.29 (0.67–2.48) |
| Chlorpyrifosb | 1.22 (0.48–3.06) | 1.75 (0.86–3.60) | 2.37 (1.08–5.19) |
| Covariates | |||
| Race/ethnicityc | 1.06 (0.48–2.38) | 0.47 (0.26–0.87) | 0.35 (0.17–0.72) |
| Genderd | 1.66 (0.80–3.44) | 1.68 (0.96–2.92) | 1.90 (1.04–3.48) |
| Gestational age | 1.00 (0.79–1.27) | 0.89 (0.72–1.10) | 0.81 (0.65–1.01) |
| Maternal IQe | 1.02 (0.98–1.05) | 0.99 (0.96–1.01) | 1.01 (0.99–1.04) |
| Low maternal educationf | 1.49 (0.69–3.22) | 0.95 (0.52–1.73) | 1.40 (0.74–2.67) |
| HOME score | 0.96 (0.89–1.02) | 0.96 (0.92–1.01) | 0.90 (0.85–0.96) |
Sample sizes for age-specific models ranged from 225 to 228 because of missed and/or unscorable assessments (<50).
a
Prenatally exposed = 1; not exposed = 0.
b
High exposure (>6.17 pg/g) = 1; low exposure (≤6.17 pg/g) = 0.
c
Black = 2; Dominican = 1.
d
Male = 2; female = 1.
e
Measured with the Test of Nonverbal Intelligence, Second Edition,42 natural logarithmically transformed.
f
No high school degree = 1; high school degree = 0.