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. Author manuscript; available in PMC: 2012 Jul 6.
Published in final edited form as: Mar Genomics. 2009 Jul 3;2(2):85–98. doi: 10.1016/j.margen.2009.03.007

Figure 3.

Figure 3

Figure 3

Figure 3

Nucleotide sequence alignments of the 30 forward (A), 22 reverse (B) and combined (C) HDS S regions. Spec2a S region is numbered 1a (sixth row). Individual nucleotides are color coded for ease of visualization. Dashed lines represent gaps. The overall consensus sequence is shown as a histogram and the consensus nucleotides are shown beneath the histogram. The cis-regulatory elements found in the 78-bp core enhancer of Spec2a are shown as colored bars underneath the consensus sequence. Red, proximal Otx-Gsc and Otx-Gsc-GataE elements; blue, OER element; green, CBF element. Reverse S region alignments in (B) are shown without the first large indel. Reverse S region alignments containing this indel are provided in Supplemental Figure S1. Sequences in (C) were aligned by artificially reversing the reverse orientation sequence blocks in the 22 HDS S regions.