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GZ-793A substitution. Rats did not differentially self-administer GZ-793A (0.01–0.3 mg/kg/infusion) relative to saline control. Baseline infusions represent self-administration of METH (0.03 mg/kg/infusion); sessions 1–21 represent substitution of varying unit doses of GZ-793A or saline; sessions 22–26 represent reinstatement of METH (0.03 mg/kg/infusion) self-administration, n=7/group
