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| IC50 (nM) | |
|---|---|
| VEGFR1 | 1.2 |
| VEGFR2 | 0.25a |
| VEGFR3 | 0.29 |
| PDGF-ß | 1.6/2.5 |
| c-KIT | 1.7/2.0 |
Note:
Noncellular IC50 values determined from biochemical assays.
Abbreviations: IC50, half maximum inhibitory concentration; VEGFR, vascular endothelial growth factor receptor; PDGF, platelet-derived growth factor; c-KIT, tyrosine-protein kinase Kit.
