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. 2012 Jul 1;87(1):165–170. doi: 10.4269/ajtmh.2012.11-0713

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©The American Society of Tropical Medicine and Hygiene

This is an Open Access article distributed under the terms of the American Society of Tropical Medicine and Hygiene's Re-use License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Quantitative sensitivity of dried blood spots (DBS) compared with plasma for detection of dengue virus (DENV)-specific antibody and viral RNA. (A) The DENV-immunoglobulin (Ig) M and -IgG capture (MAC/GAC) enzyme-linked immunosorbent assay (ELISA) Units, as a proxy for antibody quantity, are shown for paired plasma and DBS samples collected at hospital discharge from acute dengue patients. (B) The reciprocal of the cycle threshold (ct) value in DENV serotype-specific reverse transcription-polymerase chain reaction (RT-PCR), as a proxy for RNA quantity, is shown for paired plasma and DBS samples collected at hospital admission from acute dengue patients.

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