Table 2.

Production of IFN-γ against Leishmania (Leish) antigens A, B, or C by volunteers in areas of Iran endemic for ZCL, ZVL, and ACL^*

Area	IFN-γ to mitogen	IFN-γ to Leish C	IFN-γ to Leish B	IFN-γ to Leish A
ZCL-1	14.901 ± 0.40	–	1.813 ± 0.369	1.573 ± 0.316
ZCL-2	18.444 ± 1.419	1.104 ± 0.230	–	1.000 ± 0.169†
ACL	17.069 ± 0.643	1.464 ± 0.482	–	1.454 ± 0.559
ZVL	19.551 ± 0.856	2.238 ± 0.551	–	2.664 ± 0.606†

^*Values are mean ± SE (IU/mL). IFN-γ = interferon-γ; ZCL = zoonotic cutaneous leishmaniasis; ACL = anthroponotic cutaneous leishmaniasis; ZVL = zoonotic visceral leishmaniasis.

^†A statistically significant difference was shown between IFN-γ production against Leish Aantigen between persons who were cured of ZVL and healed cases of ZCL-2 (P = 0.029).