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Neurodegeneration in zCDC48-deficient embryos. Staining with Fluoro-Jade C, used as a histological marker of neurodegeneration, was performed. Neurodegeneration was detected in the eyes and brains of zCDC48-injected embryos (yellow arrowhead). The white boxes are magnified. I and II denote the cutting position, as described below. Sections were counterstained with DAPI. Scale bars, 100 μm in each panel and 10 μm in magnified panels.
