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Accumulation of polyubiquitinated proteins in the zCDC48 morphant. Cross-sections of embryos were stained with the anti-polyubiquitinated protein antibody and Fluoro-Jade C (a marker of neurodegeneration). The cells that contained polyubiquitinated proteins colocalized with the Fluoro-Jade C-positive cells in the diencephalon and eye. The sections in white boxes are magnified. Sections were counterstained with DAPI. Scale bar, 50 μm.
