. 2012 Jul 6;7(7):e40232. doi: 10.1371/journal.pone.0040232

Table 4. Cox proportional hazard model for prognosis of HD patients at a four-year follow-up.

		Univariate^a				Multivariate^a
Factor^b		95% CI^c				95% CI
	HR^d	Lower	Upper	p Value	HR	Lower	Upper	p Value
ELISA - Vitamin D binding protein, 10 mg/L	0.895	0.817	0.980	0.013^*	0.843	0.756	0.951	0.006
Age, year	1.045	1.003	1.089	0.037^*	1.048	1.005	1.092	0.027
Male gender, %	1.445	0.538	3.883	0.465
Dialysis vintage, years	0.900	0.800	1.013	0.080^*
Body weight, Kg	1.046	0.986	1.109	0.137
Height, cm	1.048	0.987	1.113	0.129
Body mass index, kg/m²	1.040	0.889	1.217	0.620
Systolic blood pressure, mmHg	1.011	0.978	1.045	0.514
Diastolic blood pressure, mmHg	1.008	0.942	1.079	0.823
Smoking index	1.167	0.795	1.712	0.430
Medications
ACE inhibitor/ARB, %	1.132	0.403	3.183	0.936
Vitamin D₃, %	1.079	0.347	3.353	0.895
Laboratory data
Leukocyte count, ×10³/µL	1.000	0.999	1.000	0.117
Hemoglobin, g/dL	1.011	0.684	1.495	0.954
Hematocrit, %	1.012	0.887	1.154	0.863
Albumin, g/dL	0.162	0.020	1.328	0.090^*	0.064	0.008	0.574	0.012
Blood urea nitrogen, mg/dL	1.005	0.973	1.038	0.752
Creatinine, mg/dL	1.134	0.648	1.983	0.660
Sodium, meq/dL	1.023	0.835	1.254	0.826
Potassium, meq/dL	1.464	0.721	2.973	0.291
Fasting blood sugar, mg/dL	1.016	0.990	1.042	0.226
Total cholesterol, mg/dL	0.998	0.985	1.012	0.777
HDL-C, mg/dL	1.001	0.972	1.032	0.939
LDL-C, mg/dL	0.992	0.980	1.004	0.210
ApoB, mg/dL	0.985	0.966	1.005	0.147
Lp(a), mg/dL	1.005	0.947	1.067	0.875
Triglycerides, mg/dL	1.001	0.997	1.005	0.557
Uric acid, mg/dL	0.821	0.576	1.170	0.275
Alanine aminotransferase, U/L	1.008	0.982	1.036	0.542
γ-glutamyl transferase, U/L	0.999	0.982	1.017	0.906
Alkaline phosphatase, U/L	1.004	0.997	1.011	0.231
Calcium, mg/dL	0.591	0.332	1.052	0.074^*
Phosphate, mg/dL	1.162	0.789	1.713	0.447
Calcium × Phosphate product	1.003	0.964	1.044	0.876
Intact-parathyroid hormone, pg/mL	1.001	1.000	1.003	0.157
25(OH) Vitamin D, ng/mL	1.033	0.973	1.096	0.289
Kt/V	0.026	0.002	0.545	0.124

Values are expressed as mean ± SD or percent.

ACE, angiotensin converting enzyme; ARB, angiotensin receptor blocker.

CI, confidence interval.

HR, hazard ratio.

p<0.10 in univariate Cox regression analysis.