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. 2012 Jul 6;7(7):e40312. doi: 10.1371/journal.pone.0040312

Figure 3. Lef1 knockout mice do not develop endometrial glands.

Figure 3

(Two vertical columns left) H&E photomicrographs of uteri from wild-type ICR mice on post-natal days (PNDs) 3, 5, 7, and 9. Wild-type uterus at PNDs: (A, B) 3, (E, F) 5, (I, J) 7, and (M, N) 9; magifications for each PND are 200× and 400×, respectively. Note that endometrial glands are visible on PNDs 7 and 9 (dashed circles). (Two vertical columns right) H&E photomicrographs of uteri from Lef-1 knockout mice on PNDs 3, 5, 7 and 9, demonstrating that endometrial glands fail to form during this period. Lef1 knockout uterus on PNDs: (C, D) 3, (G, H) 5, (K, L) 7, and (O, P) 9; magnifications for each PND are 200× and 400× respectively.