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RXRα was downregulated in human colon adenocarcinomas. Picture (1) shows a normal human colon tissue stained for RARβ. (2) shows a human adenocarcinoma stained for RARβ. RAR β is extensively expressed in the adenocarcinoma. (3) RXRα staining in normal human colon tissue. (4) RXRα staining in a human adenocarcinoma.
