Table 2.

Downregulated DEGs associated with ER stress at 24 weeks with respective array FC and a brief description of function in ER stress

Entrez ID	Symbol	Name	FC	Description
67838	Dnajb11	DnaJ (Hsp40) homologue, subfamily B, member 11	0.75	ER HSPA5 co-chaperone [47]
13198	Ddit3	DNA-damage inducible transcript 3 (CHOP)	0.8	ER stress TF [8, 10]
22433	Xbp1	X-box binding protein 1	0.8	ER stress TF [8, 10]
268390	Ahsa2	AHA1, activator of heat shock protein ATPase homologue 2 (yeast)	0.82	ER HSP90 co-chaperone homologue [48]
67475	Ero1b	ERO1-like beta (S. cerevisiae)	0.83	ER stress induced oxidoreductin [8]
14828	Hspa5	Heat shock protein 5 (BiP, GRP78)	0.84	ER stress chaperone [8, 10]
22027	Hsp90b1	Heat shock protein 90, beta (GRP94), member 1	0.84	ER stress chaperone [8]
100037258	Dnajc3	DnaJ (Hsp40) homologue, subfamily C, member 3 (p58)	0.84	ER stress co-chaperone [8]
81500	Sil1	Endoplasmic reticulum chaperone SIL1 homologue (S. cerevisiae)	0.87	ER stress HSPA5 co-chaperone/nuclear exchange factor [8]

TF, transcription factor