Table 3.
Semen quality of 4867 young men from the general population in the Copenhagen area in Denmark
| Mean (SD) | Median (5–95) | p Values comparing |
|||
| All periods | 2001–2005 vs 2006–2010 | 1996–2000 vs 2006–2010 | |||
| Semen volume (ml) | |||||
| Investigation period 1996–2010 | 3.4 (2.0) | 3.2 (1.3–6.0) | |||
| Investigation period 1996–2000 | 3.3 (1.5) | 3.1 (1.2–5.8) | |||
| Investigation period 2001–2005 | 3.3 (1.4) | 3.2 (1.4–5.9) | |||
| Investigation period 2006–2010 | 3.6 (3.1) | 3.3 (1.3–6.3) | 0.004 | 0.011 | 0.001 |
| Sperm concentration (million/ml) | |||||
| Investigation period 1996–2010 | 60 (57) | 45 (3–163) | |||
| Investigation period 1996–2000 | 58 (55) | 43 (3–167) | |||
| Investigation period 2001–2005 | 60 (58) | 45 (3–156) | |||
| Investigation period 2006–2010 | 62 (55) | 48 (3–169) | 0.065 | 0.12 | 0.020 |
| Total sperm count (million) | |||||
| Investigation period 1996–2010 | 193 (232) | 143 (9–529) | |||
| Investigation period 1996–2000 | 185 (184) | 132 (6–531) | |||
| Investigation period 2001–2005 | 191 (241) | 146 (8–508) | |||
| Investigation period 2006–2010 | 206 (258) | 151 (13–559) | 0.002 | 0.015 | 0.001 |
| Normal morphology (%) | |||||
| Investigation period 1996–2010 | 7.1 (4.9) | 6.5 (0.5–16.0) | |||
| Investigation period 1996–2000 | 7.3 (5.1) | 7.0 (1.0–17.0) | |||
| Investigation period 2001–2005 | 6.9 (4.8) | 6.0 (0.5–15.5) | |||
| Investigation period 2006–2010 | 7.5 (4.9) | 7.0 (0.5–16.0) | 0.016 | 0.023 | 0.97 |
| Total normal spermatozoa (million) | |||||
| Investigation period 1996–2010 | 16.3 (23.9) | 8.4 (0.0–57.4) | |||
| Investigation period 1996–2000 | 16.5 (24.5) | 7.9 (0.0–60.9) | |||
| Investigation period 2001–2005 | 15.5 (22.6) | 8.0 (0.0–53.8) | |||
| Investigation period 2006–2010 | 17.9 (25.3) | 9.8 (0.1–59.3) | 0.040 | 0.012 | 0.076 |
| Progressively motile (%) | |||||
| Investigation period 1996–2010 | 56 (17) | 59 (23–77) | |||
| Investigation period 1996–2000 | 54 (17) | 57 (22–75) | |||
| Investigation period 2001–2005 | 57 (17) | 60 (22–77) | |||
| Investigation period 2006–2010 | 57 (16) | 59 (25–79) | <0.0005 | 0.30 | 0.005 |
| Motile (%) | |||||
| Investigation period 1996–2010 | 65 (15) | 68 (35–83) | |||
| Investigation period 1996–2000 | 65 (15) | 68 (38–82) | |||
| Investigation period 2001–2005 | 64 (15) | 67 (35–82) | |||
| Investigation period 2006–2010 | 65 (16) | 68 (33–85) | 0.17 | 0.09 | 0.71 |
5–95: 5–95 percentiles.
p Values: Obtained from regression analysis taking confounders into consideration.