Table 3.
The Polymorphisms of the GEMIN4 Gene and the Risk of Prostate Cancer
| |
|
Patients (N=300) |
Controls (N=244) |
|
||
|---|---|---|---|---|---|---|
| Polymorphism | N | % | n | % | OR (95% CI) | |
| CC | 10 | 3.33 | 19 | 7.79 | 1 | |
| CT | 98 | 32.67 | 81 | 33.20 | 2.29 (0.95, 5.84) | |
| TT | 192 | 64.00 | 144 | 59.02 | 2.53 (1.07, 6.28) | |
| C | 118 | 19.67 | 119 | 24.39 | 1 | |
| rs7813 | T | 482 | 80.33 | 369 | 75.61 | 1.32 (0.98, 1.78) |
| TT | 259 | 86.33 | 201 | 82.37 | 1 | |
| TA/AA | 41 | 13.67 | 43 | 17.62 | 0.74 (0.45, 1.21) | |
| T | 559 | 93.17 | 445 | 91.19 | 1 | |
| rs4968104 | A | 41 | 6.83 | 43 | 8.81 | 0.76 (0.47, 1.22) |
| CC | 188 | 62.67 | 142 | 58.20 | 1 | |
| CT | 92 | 30.67 | 82 | 33.61 | 0.85 (0.58, 1.25) | |
| TT | 20 | 6.67 | 20 | 8.20 | 0.76 (0.37, 1.54) | |
| C | 468 | 78.00 | 366 | 75.00 | 1 | |
| rs3744741 | T | 132 | 22.00 | 122 | 25.00 | 0.85 (0.63, 1.13) |
| GG | 246 | 82.00 | 182 | 74.60 | 1 | |
| GC/CC | 54 | 18.00 | 62 | 25.40 | 0.64 (0.42, 0.99) | |
| G | 546 | 91.00 | 426 | 87.30 | 1 | |
| rs2740348 | C | 54 | 9.00 | 62 | 12.70 | 0.64 (0.42, 0.99) |
| TT | 298 | 99.33 | 240 | 98.36 | 1 | |
| TC/CC | 2 | 0.67 | 4 | 1.64 | 0.40 (0.04, 2.84) | |
| T | 598 | 99.67 | 484 | 99.18 | 1 | |
| rs1062923 | C | 2 | 0.33 | 4 | 0.82 | 0.40 (0.04, 2.84) |
| CC | 23 | 7.67 | 18 | 7.37 | 1 | |
| CG | 135 | 45.00 | 103 | 42.21 | 1.03 (0.49, 2.10) | |
| GG | 142 | 47.33 | 123 | 50.40 | 0.90 (0.44, 1.84) | |
| C | 181 | 30.17 | 139 | 28.48 | 1 | |
| rs910925 | G | 419 | 69.83 | 349 | 71.52 | 0.92 (0.70, 1.21) |
| CC | 240 | 80.00 | 190 | 77.87 | 1 | |
| CT/TT | 60 | 20.00 | 54 | 22.13 | 0.88 (0.57, 1.36) | |
| C | 540 | 90.00 | 434 | 88.93 | 1 | |
| rs910924 | T | 60 | 10.00 | 54 | 11.07 | 0.89 (0.59, 1.34) |
The bold numbers mean the p-value is <0.05.
OR, odds ratio; CI, confidence interval.