Table 4.
Haplotypes and the Risk of Prostate Cancer
| |
Cases (N=300) |
Controls (N=244) |
|
|
||
|---|---|---|---|---|---|---|
| Haplotype | n | % | n | % | OR (95% CI) | P |
| H1 (MWWWWMW) | 107 | 35.67 | 60 | 24.59 | 1 | |
| H2 (MWMWWMW) | 65 | 21.67 | 50 | 20.49 | 0.73(0.44, 1.22) | 0.20 |
| H3 (MWWMWMW) | 23 | 7.67 | 26 | 10.66 | 0.50(0.25, 0.99) | 0.03 |
| H4 (MMWWWMM) | 19 | 6.33 | 19 | 7.79 | 0.56(0.26, 1.22) | 0.11 |
| H5 (MWMMWMW) | 14 | 4.67 | 18 | 7.38 | 0.44(0.19, 1.00) | 0.03 |
| H6(MMMWWMM) | 13 | 4.33 | 12 | 4.92 | 0.61(0.24, 1.56) | 0.25 |
| H7 (MWWWWMM) | 8 | 2.67 | 4 | 1.64 | 1.12(0.29, 5.30) | 0.86 |
| Others | 51 | 17.00 | 55 | 22.54 | - | - |
The haplotype analysis was in the order of rs7813, rs4968104, rs3744741, rs2740348, rs1062923, rs910925, and rs910924.
The bold numbers mean the p-value is <0.05.
W, wild genotypes; M, heterozygous and mutant homozygous genotypes.