Table 2.
Correlation between magnitude of epitope-specific response and HIV-1 percent suppression at E:T of 1:1.
Ex vivo response |
In vitro response (Expanded lines) |
|||
---|---|---|---|---|
Spearman coefficient (r) |
P value | Spearman coefficient (r) |
P value | |
CD107a+ | 0.17 | 0.58 | 0.36 | 0.18 |
IFN-γ+ | 0.08 | 0.80 | 0.27 | 0.32 |
IL-2+ | −0.16 | 0.62 | 0.19 | 0.48 |
TNF-α+ | 0.19 | 0.54 | 0.27 | 0.32 |
Perforin+ | 0.32 | 0.30 | 0.31 | 0.25 |
Polyfunctional (≥3 functions) | 0.26 | 0.40 | 0.26 | 0.34 |
Polyfunctional + IL-2 production | 0.51 | 0.09 | 0.56 | 0.03 |