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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Biol Psychiatry. 2012 Jan 3;72(1):57–64. doi: 10.1016/j.biopsych.2011.11.022

Figure 3.

Figure 3

Using whole-brain voxel-based morphometry, more cumulative adverse life events and greater chronic stress were associated with lower mean gray matter volume (familywise error p <.001; x = 4.5, y = 22.5, z = −12.5), after controlling for age, sex, and total intracranial volume and the main effects of both scales in a region (7175 voxels) of the orbitofrontal cortex, anterior cingulate, insula, and subgenual areas. The regression interaction is depicted in the graph.