Table 2.
Re-measurement error (precision) for mean cartilage thickness over the total area of bone (ThCtAB.Me) from unpaired analyses represented as RMSE CV%, for each cartilage plate, analysis team and acquisition for (A) medial and lateral tibia, (B) medial and lateral central femur. The combined (pooled data) RMSE CV% for a plate and acquisition combination were computed with and without the results from outlier teams. Metrics where a significant team effect on precision was observed had outlier teams identified by results that differed significantly from at least 2 other teams in pair-wise comparisons. Two isolated test-retest outlier pairs for ThCtAB.Me were excluded from MT analyses of DESS-MPR, for cMF and cLF analyses of FLASH and from cMF analyses of DESS-MPR.
| (A) Medial and Lateral Tibia (MT and LT) mean cartilage thickness over the total area of bone (ThCtAB.Me) | ||||||
|---|---|---|---|---|---|---|
| MT | LT | |||||
| Analysis Team |
FLASH | DESS- MPR |
DESS | FLASH | DESS- MPR |
DESS |
| B | 1.8% | 3.1% | 2.9% | 2.3% | 2.2% | 2.0% |
| C | 3.1% | 3.4% | 2.1% | 3.4% | 2.4% | 2.7% |
| D | -- | -- | -- | -- | -- | -- |
| E | 6.8% | 7.3% (4.7%) | 3.0% | 4.1% | 4.6% | 3.1% |
| Pooled, without isolated outlier data points | - | 3.6% (0.08) | - | - | - | - |
| Pooled, without outlier team | - | 3.3% | - | - | - | - |
| Pooled (p-value for team effect) [RMSE mm] | 4.6% (0.06) [0.09] | 5.1% 1 (0.04) [0.09] | 2.7% (0.89) [0.05] | 3.4% (0.64) [0.08] | 3.4% (0.07) [0.08] | 2.6% (0.02) [0.06] |
| (B) Central Medial and Lateral Femur (cMF and cLF) mean cartilage thickness over the total area of bone (ThCtAB.Me) | ||||||
|---|---|---|---|---|---|---|
| cMF | cLF | |||||
| Analysis Team |
FLASH | DESS- MPR |
DESS | FLASH | DESS- MPR |
DESS |
| B | 2.4% | 3.7% | 2.8% | 3.8% | 3.7% | 2.9% |
| C | 4.5% | 4.5% | 3.0% | 4.1% | 3.8% | 3.4% |
| D | 3.5% | 4.0% | 1.8% | 3.4% | 3.1% | 2.8% |
| E | 7.6% (5.9%) | 9.7% (7.6%) | 4.8% | 6.8% (5.6%) | 6.6% | 6.6% |
| Pooled, without isolated outlier data points | 4.1% (0.11) | 5.1% (0.14) | - | 4.2% (0.14) | - | - |
| Pooled, without outlier team | - | - | - | - | 3.5% | 3.0% |
| Pooled (p-value for team effect) [RMSE mm] | 4.7% (0.06) [0.09] | 5.9% (0.06) [0.11] | 3.3% †† (0.05) [0.06] | 4.6% (0.13) [0.08] | 4.4% 2 (0.004) [0.08] | 4.2% 2 (0.04) [0.08] |
P<0.01 for acquisition differences within a plate, all teams combined. DESS-MPR versus FLASH, P= 0.07; DESS-MPR versus DESS P<0.01.
Team B and C differ (p<0.05) from E; after outlier data point removal B–C=0.12 and C–E=0.03
Team B and D differ (p<0.05) from E; after outlier data point removal MPR: B–E=0.01 and D–E=0.006, DESS: B–E=0.02, and D–E=0.009