Table 4.

The T and C variants of 3′-UTR single-nucleotide polymorphisms (rs2235749) oligonucleotides, and E-box oligonucleotides used in an EMSA. E-box consensus sequence is CANNTG, where N denotes any nucleotide (Seo et al. 2007; Kee 2009). T- and G-boxes are variants of E-box.

	Sequence	DNA targetelement
T-UTRa	TGGCCCAACATA-T-GCACTGGGCAT	T-box
C-UTR	TGGCCCAACATA-C-GCACTGGGCAT	mutant T-box
5mC-UTR	TGGCCCAACATA-5mC-GCACTGGGCAT
PD-Prb	CGGGCCATGCACGTGCCTGCTGAC	G-box
E–boxc	CGTGCGGCCTGACAGGTGCTTTGA	E-box
mE-box d	CGTGCGGCCTGCACACTGCTTTGA	mutant E-box

E-box and its variant are underlined. T, C and ^5mC alleles of the 3′-UTR are shown in bold.

^a,bT- and G-boxes are present in the T allele 3′-UTR and PDYN promoter (PD-Pr) oligonucleotides.

^cE-box sequence was taken from the SMU gene (Kataoka et al. 2000).

^dNucleotides destroying E-box are shown in italic.