Figure 5.

Firing Modulation with Hippocampal Theta Oscillations and Responses to Noxious Stimuli Are Cell Type Specific

(A) Cell types mean θ phase histograms. CB⁺ dendrite-targeting interneurons are homogeneously and strongly modulated in phase with dCA1 θ, in contrast to the other cell types. Two θ cycles are represented for clarity. 0°, 360°, and 720°: θ troughs.

(B) Polar distribution of individual neurons' preferred θ phases and modulation depths. Each symbol represents a significantly modulated cell.

(C and D) Cell types mean peristimulus histograms for noxious stimulation. Axo-axonic cells are dramatically excited and AStria-projecting cells are inhibited by electrical shocks and pinches delivered to the controlateral hindpaw. Error bars: SEM; dashed lines: mean ± 2 standard deviations. n values represent the number of neurons tested in each analysis.

See also Figures S2, S4, and S5.