Expression of UPR mRNAs in WT animals after SCI. Transcript levels of ATF4 (A), GADD34 (B), GRP78 (C), CHOP (D), and DR5 (E) mRNAs were normalized to Gapdh and expressed as fold changes compared with levels in sham controls post-SCI. Significant differences in expression levels of UPR mRNAs between injury epicenter and rostral segments are indicated. Data are the mean ± SD (n = 4, *P < 0.05, **P < 0.01).