Figure 5.

Effects of the 4th fraction of Nardostachys jatamansi pretreatment on pancreatic weight/body weight (A), serum amylase activity (B), and serum lipase activity (C) during cerulein-induced acute pancreatitis. Mice pretreated with Nardostachys jatamansi (NJ) were challenged with intraperitoneal injections of cerulein (50 μg/kg). Mice were killed 6 h after the last cerulein injection. Their serum and pancreas were harvested and (A) pancreatic weight (PW)/body weight (BW) ratio and the levels of digestive enzymes such as (B) amylase and (C) lipase were measured as indicated in the experimental protocol. Data show the mean ± SE for 6 mice in 1 group. The results were similar in 3 additional experiments. ^aP < 0.05 vs the saline treatment; ^cP < 0.05 vs cerulein treatment alone. AP: Acute pancreatitis.