Table 4.
Diagnostic criteria for infective endocarditis (IE)
| Definite IE | Possible IE | Rejected IE |
|---|---|---|
|
Clinical criteria 2 Major criteria or 1 major and 3 minor criteria Or 5 minor criteria |
1 major and 1 minor criteria Or 3 minor criteria |
Alternate diagnosis Resolution of the infection with antibiotic treatment for <4 days No histological evidence |
|
Definition of terms Major criteria 1. Positive blood cultures 2. Evidence of endocardial involvement (TTE/TEE; histological specimen) 3. New valvular regurgitation (clinical modification of pre-existing murmur not enough) Minor criteria 1. Predisposition (previous IE, predisposing heart condition, injection drug use) 2. Fever, temperature >38 ° C 3. Vascular phenomena 4. Immunologic phenomena 5. Microbiological evidence: positive BC that not met major criteria characteristics Echocardiographic minor criteria eliminated "St Thomas" minor criteria, proposed by Lamas & Eykyn, not added but helpful in judgement: CRP > 100 mg/l, ESR elevation, splenomegaly, haematuria, clubbing, splinter haemorrhagia, petechiae and purpura, central non-feeding venous lines, peripheral venous lines (18) | ||