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ATRA stimulates ABCA1-mediated cholesterol efflux. Activated CD4+ T cells were treated with DMSO or 5 μM ATRA and loaded with radioactive cholesterol for 24 hours and cholesterol efflux to apo-A1 was estimated after 4 hours incubation in cholesterol efflux medium. The result is presented as mean ± the standard deviation (SD; n = 3). * p < 0.05 versus cells treated with DMSO.
